All seizures were recorded by parents or caregivers in paper journals that were reviewed by the study team in each clinical control. Tolerability and adverse effects were evaluated every 2 weeks using the Liverpool Adverse Events Profile or the Adverse Effects Questionnaire in Pediatric Epilepsy, depending on age.
The additional variables measured prospectively in the patients' diaries were the use of rescue medications, epileptic status episodes, and emergency room visits or hospital admissions CBD Gummies. Laboratory studies were carried out for hematology, electrolytes, liver and kidney function and concentrations of antiepileptic drugs and cannabidiol at the beginning and after 4, 8 and 12 weeks of treatment with cannabidiol,
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